Acetyl-L-Carnitine (500 mg) - 90 Capsules

Description 

Klaire Labs Acetyl-L-Carnitine (500 mg)

Neurological Support

L-carnitine derivative that helps maintain brain and nerve function during aging. It may benefit membrane stability, nerve growth factor, and cerebral blood flow.

Research on this acetylated derivative of L-carnitine has centered largely on its role in maintaining brain and nerve function during aging. The acetyl group improves transport across the blood-brain barrier, while the L-carnitine component carries fatty acids into the mitochondria of nerve cells for use in energy production. Other actions benefit membrane stability, the production of nerve growth factor, and cerebral blood flow. Several clinical trials have demonstrated that ALC supplementation preserves and improves overall cognitive function in the elderly.

Benefits and Features:

• Support for healthy nerve and brain function especially during aging.

Ingredients

Other Ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), microcrystalline cellulose, L-leucine, and silicon dioxide.

Made without common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and sesame. Non-GMO, Vegan, No synthetic colors, flavors, or preservatives.

Suggested Use

Adults: 1 capsule, 1 to 3 times daily or as directed by a healthcare professional.

Children: As directed by a healthcare professional.

Caution: If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product. KEEP OUT OF REACH OF CHILDREN.

More Info.

Supports healthy cerebral aging and nerve function.

Acetyl L-carnitine (ALC) is a physiologic peptide crucial for fatty acid transport. It is an ester of the amino acid derivative L-carnitine and has been shown in preclinical and clinical research to support healthy cognitive function, concentration and focus, enhance nerve cell function, regenerate peripheral nerve cells, provide antioxidant protection, and promote cellular energy production. It also plays a major role in the healthy functioning of the mitochondria. It is also required for helping transport fatty acids into the mitochondria, where they can be used as fuel. Acetyl L-carnitine supports cardiovascular health by providing antioxidant protection and promoting cellular energy production and has been shown to support the reproductive system.

The addition of the acetyl group in ALC improves transport across the blood-brain barrier. Although the precise mechanisms of action are unknown, research indicates that its influence may be related to its effects on neural transmission and cellular energy metabolism. A study of the antioxidant activity of ALC in the central nervous system found that supplementation with attenuated protein oxidation and lipid peroxidation also enhanced the activity of other antioxidants at the same time. Animal research suggests a protective effect of ALC on aging neurons, and that this effect might be mediated by its antioxidant activity. Acetyl L-carnitine also appears to improve spatial working memory in animal research. It may also support healthy cellular function in aging by increasing cellular ATP production, as well as affect Nerve Growth Factor.

Most importantly, several clinical trials have demonstrated that ALC supplementation preserves and improves overall cognitive function in the elderly. In a controlled clinical trial, ALC was given to elderly individuals with mild cognitive complaints. After 45 days of supplementation at 1,500 mg/d, significant improvements in cognitive function (especially memory) were observed. Another large clinical trial of ALC in a similar group of elderly individuals found that 1,500 mg/d for 90 days significantly improved memory, mood, and responses to stress. The favorable effects lasted at least a month after treatment was discontinued. Other controlled and open-label clinical trials have corroborated these findings.